Increased suppression of conservative voices is my vote (and a second for Critical Race Theory)
But the list is so long:
Endless lockdowns due to virus panic
More and increased government corruption
Increased climate hysteria
Green energy economic destruction (not to mention the corruption inherent in government green money/business)
Insane judges
Higher Taxes
Rise of China
Increased bureaucracy
Critical Race Theory and continued targeting of "privileged" groups
Increased Immigration
The list goes on and on...but those are what I see as the worst ones.
The worst thing about a Biden presidency is the Harris presidency that comes after it.