I've got one that is at every major family gathering and she's fine - until she starts jamming her inane hyper progressive worldview into every conversation and acting like it's normal and anyone who disagrees is a troglodyte.

As a woman myself, it gets really old. She only gets away with it because she's a chick. She also acts like she hates conflict, so she'll get to duck out of any kind of a ruckus she starts, but has no problem stirring the pot. It's super disrespectful.