Do you have any concerns at all about this new mRNA method of vaccinating a population? This is the last article I found on JAMA, the news seems good but the caveat is always that this is new and untested on humans for a long enough period of time:
Not over the use of mRNA. My primary concerns are with the PEGylated lipid nanoparticles. These seem to be the source of adverse reactions, sometimes serious, and are the reason why this untested vaccine is somewhat concerning.
The science behind mRNA vaccination is fairly sound and has been considered since circa 1989 for cancer treatment. As far as I understand, there have been attempts since 2005 to manufacture it, but all of them were hampered by the inability to consistently devise a delivery mechanism to get the mRNA into the cytoplasm of the cells.
The idea of encapsulating mRNA inside lipid nanoparticles is fairly new. That's the part that's untested, and unfortunately seems to be the most dangerous aspect.
Do you have any concerns at all about this new mRNA method of vaccinating a population? This is the last article I found on JAMA, the news seems good but the caveat is always that this is new and untested on humans for a long enough period of time:
https://jamanetwork.com/journals/jama/fullarticle/2770485
Not over the use of mRNA. My primary concerns are with the PEGylated lipid nanoparticles. These seem to be the source of adverse reactions, sometimes serious, and are the reason why this untested vaccine is somewhat concerning.
The science behind mRNA vaccination is fairly sound and has been considered since circa 1989 for cancer treatment. As far as I understand, there have been attempts since 2005 to manufacture it, but all of them were hampered by the inability to consistently devise a delivery mechanism to get the mRNA into the cytoplasm of the cells.
The idea of encapsulating mRNA inside lipid nanoparticles is fairly new. That's the part that's untested, and unfortunately seems to be the most dangerous aspect.
Thanks so much for such a comprehensive answer, I appreciate it!