I would say the very small chance of treatable anaphylaxis is worth ending a pandemic and getting back to normal life. I’d also argue that mRNA nanoparticles offer better protection against mutated strains than live attenuated viruses.

Oh, and I meant to address this too. You're absolutely right. We need to do something, even if it gives some percentage of the population the confidence to open everything back up. The economic disaster unfolding in every state (especially mine) because of these draconian lockdown measures will almost certainly kill more people than the pandemic ever could.

I do have a question for you. Moderna claimed that their tooling is such that once the Chinese released the sequence genome of the virus, they were able to a) pinpoint the receptor sites to target for a vaccine and b) manufactured it in about 2 days since they're able to chemically synthesize the mRNA. Their explanation for it taking so many months since January to release the vaccine is due to federal regulations and the required trials.

Is this true? It seems to me that if that's the case and we can demonstrate that lipid nanoparticles are a comparatively safe delivery system, almost anything could effectively be vaccinated against in short order provided it has structures the immune system can recognize that are also possible to generate from within infected cells via mRNA.

That seems... groundbreaking, to be completely honest, and may be one of the most important breakthroughs in medical history.

Likewise, I agree 100%. Live attenuated vaccines and inactivated vaccines seem grossly inefficient compared to mRNA vaccinations, which in my understanding appear to be highly targeted with the advantage of a very short time to manufacture!