ITT: People who have no idea how mRNA works. It can't be used to "splice in genes" like y'all seem to think. If it were that easy my research using retroviruses wouldn't have spectacularly failed.
Holy shit get a grip, this is not the hill to die on.
Because it is incredibly incredibly difficult to transfect any sort of DNA from retrovirus into a human cell, even in extremely controlled settings. So the gene we wanted to be placed in the cells never appeared.
I can't imagine any real way to do it with mRNA. We have ways to PCR from that but to reverse it in such a way to alter someone's DNA is just not something we are good at doing, particularly because our mRNA vaccines go no where near DNA in the first place, and the mRNA of the virus we are using isn't a self-replicating portion to begin with.
If this was actually possible it would be a massive breakthrough in the field of genetics worthy of many nobel prizes, not just one.
ITT: People who have no idea how mRNA works. It can't be used to "splice in genes" like y'all seem to think. If it were that easy my research using retroviruses wouldn't have spectacularly failed.
Holy shit get a grip, this is not the hill to die on.
how did your research fail?
Because it is incredibly incredibly difficult to transfect any sort of DNA from retrovirus into a human cell, even in extremely controlled settings. So the gene we wanted to be placed in the cells never appeared.
I can't imagine any real way to do it with mRNA. We have ways to PCR from that but to reverse it in such a way to alter someone's DNA is just not something we are good at doing, particularly because our mRNA vaccines go no where near DNA in the first place, and the mRNA of the virus we are using isn't a self-replicating portion to begin with.
If this was actually possible it would be a massive breakthrough in the field of genetics worthy of many nobel prizes, not just one.