It takes time for a constant dosage to peak -- around 3-6 wks. HCQ takes 6 months to peak its circulation throughout. Cumulative half-lives are the following:
A 200mg oral dose of hydroxychloroquine has a half life of 537 hours or 22.4 days in blood, and 2963 hours or 123.5 days in plasma
and
T<sub>4</sub> half-life is 6 to 7 days. T<sub>3</sub> half-life is 1 to 2 days.[F4636]
It takes time for a constant dosage to peak -- around 3-6 wks. HCQ takes 6 months to peak its circulation throughout. Cumulative half-lives are the following:
A 200mg oral dose of hydroxychloroquine has a half life of 537 hours or 22.4 days in blood, and 2963 hours or 123.5 days in plasma
and
T<sub>4</sub> half-life is 6 to 7 days. T<sub>3</sub> half-life is 1 to 2 days.[F4636]