"Hydroxychloroquine was studied to prevent and treat coronavirus disease 2019 (COVID‑19), but all clinical trials conducted during 2020 found it is ineffective and may cause dangerous side effects.[8][9][10][11]"
The essential conclusion: "...we recommend that HCQ only be used for COVID‐19 in the context of a carefully constructed randomized clinical trial. If this agent is used outside of a clinical trial, the risks and benefits should be rigorously weighed on a case‐by‐case basis and reviewed in light of both the immune dysfunction induced by the virus and known antiviral and immune modulatory actions of HCQ."
Conclusion: "The use of either chloroquine or hydroxychloroquine and azithromycin for treatment or prevention of SARS-CoV-2 infection is currently supported primarily by in vitro data and weak studies involving humans. Physicians and patients should be aware of several uncommon but potentially life-threatening adverse effects should these drugs be used before better-designed studies determine their benefit, if any, in treating or preventing COVID-19. Harms of treatment can be mitigated by careful patient selection and monitoring."
Conclusion: "There is sufficient pre-clinical rationale and evidence regarding the effectiveness of chloroquine for treatment of COVID-19 as well as evidence of safety from long-time use in clinical practice for other indications [3] to justify clinical research on the topic. The current circumstances justify prioritization of ethical review of study proposals above other, less pressing, research topics (i.e. fast track institutional ethical review). Although the use of chloroquine may be supported by expert opinion, clinical use of this drug in patients with COVID-19 should adhere to the MEURI framework or after ethical approval as a trial as stated by the WHO. Data from high-quality, coordinated, clinical trials coming from different locations worldwide are urgently needed."
The conclusion was that hydroxychloroquine is ineffective against SARS-COV-2. Guess what, the study was conducted in the UK. No mention of zinc in the article. To be eligible for the trial, patients had to have "clinically-suspected or laboratory-confirmed SARS-CoV-2 infection."
Hm. That could well include old folks unfortunately already on their way out. No mention about how far along in their disease they were given the hydroxychloroquine.
Conclusion: "Among patients hospitalized with COVID-19, this retrospective study did not identify any significant reduction in mortality or in the need for mechanical ventilation with hydroxychloroquine treatment with or without azithromycin."
Issues with that one. No zinc used. Treatment appears to be when folks are already hospitalized. Naturally median age around 70 though that is to be expected. I'm also seeing a fair bit of conflict of interest with those conducting the study.
Conclusion: "In this multi-hospital assessment, when controlling for COVID-19 risk factors, treatment with hydroxychloroquine alone and in combination with azithromycin was associated with reduction in COVID-19 associated mortality. Prospective trials are needed to examine this impact."
Treatment with hydroxychloroquine essentially halves deaths. And again, this is for folks who are so sick they are already being hospitalized. And no mention of zinc, which could drastically improve the efficacy of the hydroxychloroquine in combination azithromycin.
Click them. Archive them. Spread the news far and wide. This drug has been in use for many decades, and in has a stellar safety profile, with adverse events being very rare. It's too cheap. It's too effective. The fear needed to be spread. Yes, for political and financial reasons. I know many nurses and doctors are doing their best, but those at the top have conflicts of interest, and managed this situation poorly. Yes, for financial and political reasons. We can go over PCR tests another time, but let this post serve as indication that misinformation is being spread for the purpose of fear, regardless of motive.
If you want to stipulate that a half million Americans died of "Covid" (this of course is not true but let's stipulate it), then you should know that the attack on this drug is as close to the murder of hundreds of thousands of Americans as you can get.
The big lie.
Hydroxychloroquine's Wikipedia page: https://en.wikipedia.org/wiki/Hydroxychloroquine
At the bottom of the top summary paragraph:
"Hydroxychloroquine was studied to prevent and treat coronavirus disease 2019 (COVID‑19), but all clinical trials conducted during 2020 found it is ineffective and may cause dangerous side effects.[8][9][10][11]"
Click each of those 4 links referenced: Number 8: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267640/
The essential conclusion: "...we recommend that HCQ only be used for COVID‐19 in the context of a carefully constructed randomized clinical trial. If this agent is used outside of a clinical trial, the risks and benefits should be rigorously weighed on a case‐by‐case basis and reviewed in light of both the immune dysfunction induced by the virus and known antiviral and immune modulatory actions of HCQ."
Number 9: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207200/
Conclusion: "The use of either chloroquine or hydroxychloroquine and azithromycin for treatment or prevention of SARS-CoV-2 infection is currently supported primarily by in vitro data and weak studies involving humans. Physicians and patients should be aware of several uncommon but potentially life-threatening adverse effects should these drugs be used before better-designed studies determine their benefit, if any, in treating or preventing COVID-19. Harms of treatment can be mitigated by careful patient selection and monitoring."
Number 10: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270792/
Conclusion: "There is sufficient pre-clinical rationale and evidence regarding the effectiveness of chloroquine for treatment of COVID-19 as well as evidence of safety from long-time use in clinical practice for other indications [3] to justify clinical research on the topic. The current circumstances justify prioritization of ethical review of study proposals above other, less pressing, research topics (i.e. fast track institutional ethical review). Although the use of chloroquine may be supported by expert opinion, clinical use of this drug in patients with COVID-19 should adhere to the MEURI framework or after ethical approval as a trial as stated by the WHO. Data from high-quality, coordinated, clinical trials coming from different locations worldwide are urgently needed."
Number 11: https://www.bbc.com/news/world-us-canada-53575964
Just some random BBC web page saying how Fauci says it is ineffective.
The conclusion of those references do NOT support what that Wikipedia page says.
The New England journal of medicine posted a study in mid Novermber 2020: https://www.nejm.org/doi/full/10.1056/NEJMoa2022926
The conclusion was that hydroxychloroquine is ineffective against SARS-COV-2. Guess what, the study was conducted in the UK. No mention of zinc in the article. To be eligible for the trial, patients had to have "clinically-suspected or laboratory-confirmed SARS-CoV-2 infection."
Hm. That could well include old folks unfortunately already on their way out. No mention about how far along in their disease they were given the hydroxychloroquine.
The VA study: https://www.sciencedirect.com/science/article/pii/S2666634020300064?via%3Dihub
Conclusion: "Among patients hospitalized with COVID-19, this retrospective study did not identify any significant reduction in mortality or in the need for mechanical ventilation with hydroxychloroquine treatment with or without azithromycin."
Issues with that one. No zinc used. Treatment appears to be when folks are already hospitalized. Naturally median age around 70 though that is to be expected. I'm also seeing a fair bit of conflict of interest with those conducting the study.
The big Henry Ford study: https://www.ijidonline.com/article/S1201-9712(20)30534-8/fulltext
Conclusion: "In this multi-hospital assessment, when controlling for COVID-19 risk factors, treatment with hydroxychloroquine alone and in combination with azithromycin was associated with reduction in COVID-19 associated mortality. Prospective trials are needed to examine this impact."
Treatment with hydroxychloroquine essentially halves deaths. And again, this is for folks who are so sick they are already being hospitalized. And no mention of zinc, which could drastically improve the efficacy of the hydroxychloroquine in combination azithromycin.
Click them. Archive them. Spread the news far and wide. This drug has been in use for many decades, and in has a stellar safety profile, with adverse events being very rare. It's too cheap. It's too effective. The fear needed to be spread. Yes, for political and financial reasons. I know many nurses and doctors are doing their best, but those at the top have conflicts of interest, and managed this situation poorly. Yes, for financial and political reasons. We can go over PCR tests another time, but let this post serve as indication that misinformation is being spread for the purpose of fear, regardless of motive.
If you want to stipulate that a half million Americans died of "Covid" (this of course is not true but let's stipulate it), then you should know that the attack on this drug is as close to the murder of hundreds of thousands of Americans as you can get.