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RememberKosciuszko 11 points ago +11 / -0

It keeps on multiplying receptors (part of a cell that substance acts on to spark an action)

Brain constantly works to discourage use by making the thing stop working in current dose

Yet at the same time reward system makes human crave it relentlessly

Substance abuse is a vicious, hellish cycle

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deleted 4 points ago +4 / -0