The problem for viruses and these ''vaccines'' is that hydrophilic, negatively charged polynucleotides (DNA, RNA) can't pass through hydrophobic, negatively charged cell membrane. Viruses solve this by e.g. interacting with membrane receptors and tricking the cell into taking them through the membrane (receptor-mediated endocytosis)
These ''vaccines'' solve the problem by coating the RNA with hydrophobic membrane (in essence, a miniature cell membrane with just the lipid particles). This hydrophobic membrane then fuses with the cell membrane, releasing its contents into the cytoplasm.
In addition, the membrane protects the mRNA inside from enzymes called nucleases (in this case, RNAses). If the mRNA wasn't protected from these nucleases, it would be degraded pretty much instantly.
If your cells can develop antibodies normally on encountering a virus, why does this need a outer layer to get it past the cells?
The problem for viruses and these ''vaccines'' is that hydrophilic, negatively charged polynucleotides (DNA, RNA) can't pass through hydrophobic, negatively charged cell membrane. Viruses solve this by e.g. interacting with membrane receptors and tricking the cell into taking them through the membrane (receptor-mediated endocytosis)
These ''vaccines'' solve the problem by coating the RNA with hydrophobic membrane (in essence, a miniature cell membrane with just the lipid particles). This hydrophobic membrane then fuses with the cell membrane, releasing its contents into the cytoplasm.
In addition, the membrane protects the mRNA inside from enzymes called nucleases (in this case, RNAses). If the mRNA wasn't protected from these nucleases, it would be degraded pretty much instantly.