That is exactly what happens to the ODs I have to deal with, especially if they just came off of a 2-3 day run on meth, even with no other drugs, meth heads crash and can sleep for a day or two. Fentanyl, etc eventually knocks them out without anything else, usually people think they are already dead unless they breath loudly enough once in a while. We get some low O2 reading, respirations in the gutter...inhaled narcan can take 5-10 minutes sometimes, and usually it wears off. Some coworkers have given 15 doses, and even then they may still die...AEDs don't help with this shit, they only work on vFib or vTach. Just O2, CPR, and counter agents... It's all so tiresome...