COVID-19 RNA Based Vaccines and the Risk of Prion Disease
Classen JB. COVID-19 RNA Based Vaccines and the Risk of Prion Disease. Microbiol Infect Dis. 2021; 5(1): 1-3.
ABSTRACT
Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARSCoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In
this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine
recipients. The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the
potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma
(FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences
that may induce TDP-43 and FUS to fold into their pathologic prion confirmations. In the current analysis a total
of sixteen UG tandem repeats (ΨGΨG) were identified and additional UG (ΨG) rich sequences were identified. Two
GGΨA sequences were found. Potential G Quadruplex sequences are possibly present but a more sophisticated
computer program is needed to verify these. Furthermore, the spike protein, created by the translation of the vaccine
RNA, binds angiotensin converting enzyme 2 (ACE2), a zinc containing enzyme. This interaction has the potential
to increase intracellular zinc. Zinc ions have been shown to cause the transformation of TDP-43 to its pathologic
prion configuration. The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause
ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases. The
enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the
RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.
Yep, the vaccine causes your cells to manufacture proteins, the proteins travel to your brain, voila! In a year or so you will be diagnosed with incurable Mad Cow disease, a brutal death.
Do you guys know how studies work? You don’t cherry pick studies that back your point of view, you want for them to be peer reviewed and then repeated. Just like the dumb mask study that was linked here published by a PHD who claimed to be part of Standford and wasn’t. People here are spot on most issues, but when it comes to studies people here are dense and blinded by their politics.
It costs $2300 USD to peer review a study for publishing. Only research departments post studies for peer review for publishing. Long gone are the days when thinking doctors, who now make up about 1% of the profession, could interact with their peers. And the university medical, and research departments are all captured.
Hmmm. The link is broken for me; had to read a copy from the Wayback Machine. Anyone else not able to access the link now? Has this report abstract been pulled?
The Classen study “seems to be based on gibberish presented in a seemingly scientific manner.” “mRNA vaccines have a longer history of testing in humans that started several years before the COVID vaccines, and these past vaccines were found to be safe and have not resulted in prion disease, said Jacob Yount, associate professor in the Department of Microbial Infection and Immunity at Ohio State University. “Further, the mRNAs themselves are degraded by our cells in a matter of days, so I do not find any reason to think that the mRNAs delivered to cells in our arm muscle would have a direct effect on proteins in the brain.”
Vincent Racaniello, professor of microbiology and immunology at Columbia University, called the claim that messenger RNA vaccines produced by Pfizer/BioNTech and Moderna could lead to an increase in prion disease is “completely wrong,” and that Classen’s article is “flawed.” In an email to The Dispatch Fact Check he said: “The study by Classen is a theoretical exercise in which he assesses if the mRNA vaccine can convert cell proteins to prion conformations. The exercise iscompletely speculative and flawed and no conclusions can be drawn from this study. Hence the claims on social media are completely wrong as they are based on a flawed study from which no conclusions can be made.”
Animal studies have gone on since 1990. mRNA vaccines have been tested in humans before, for at least four infectious diseases: rabies, influenza, cytomegalovirus, and Zika.
The technology has been used not just in vaccines for infectious diseases, but also as a means to rev up the immune system to battle cancer. mRNA can target tumor-associated antigens expressed mainly by cancerous cells, like certain growth factors. These therapeutic -- rather than prophylactic -- vaccines have been tested in a range of cancers, including acute myeloid leukemia, multiple myeloma, glioblastoma, melanoma, prostate cancer, and others.
You know there are going to be zombies. It seems inevitable.
COVID-19 RNA Based Vaccines and the Risk of Prion Disease
Classen JB. COVID-19 RNA Based Vaccines and the Risk of Prion Disease. Microbiol Infect Dis. 2021; 5(1): 1-3.
ABSTRACT
Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARSCoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients. The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations. In the current analysis a total of sixteen UG tandem repeats (ΨGΨG) were identified and additional UG (ΨG) rich sequences were identified. Two GGΨA sequences were found. Potential G Quadruplex sequences are possibly present but a more sophisticated computer program is needed to verify these. Furthermore, the spike protein, created by the translation of the vaccine RNA, binds angiotensin converting enzyme 2 (ACE2), a zinc containing enzyme. This interaction has the potential to increase intracellular zinc. Zinc ions have been shown to cause the transformation of TDP-43 to its pathologic prion configuration. The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases. The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.
I also wonder if it will also cause issues similar to amylodosis.
Ugh, that's one of those diseases you automatically have if you look it up. Also, a favorite possible diagnosis on "House."
Yeah, but this is one of those situations where it could be the culprit.
I encourage all communist to get the jab
Where is our so-called media on this?
The Enemy of the people? Why, busy being the enemy of the people, of course!
Yep, the vaccine causes your cells to manufacture proteins, the proteins travel to your brain, voila! In a year or so you will be diagnosed with incurable Mad Cow disease, a brutal death.
The amyloid proteins attack every organ. It would be mercy if an effected man or woman just had a heart attack from amyloidosis.
Yes and if you are not yet frighten to death about this, see what this Doctor has to say. https://rumble.com/vfx0h3-german-microbiologist-they-are-killing-people-with-covid-vaccines-to-reduce.html
things are going to get real interesting -
Do you guys know how studies work? You don’t cherry pick studies that back your point of view, you want for them to be peer reviewed and then repeated. Just like the dumb mask study that was linked here published by a PHD who claimed to be part of Standford and wasn’t. People here are spot on most issues, but when it comes to studies people here are dense and blinded by their politics.
This is true, but you can’t cherry pick studies as proof of one’s viewpoint.
It costs $2300 USD to peer review a study for publishing. Only research departments post studies for peer review for publishing. Long gone are the days when thinking doctors, who now make up about 1% of the profession, could interact with their peers. And the university medical, and research departments are all captured.
Hmmm. The link is broken for me; had to read a copy from the Wayback Machine. Anyone else not able to access the link now? Has this report abstract been pulled?
So what they're saying is that they'll be returning customers. muh capitalism
The Classen study “seems to be based on gibberish presented in a seemingly scientific manner.” “mRNA vaccines have a longer history of testing in humans that started several years before the COVID vaccines, and these past vaccines were found to be safe and have not resulted in prion disease, said Jacob Yount, associate professor in the Department of Microbial Infection and Immunity at Ohio State University. “Further, the mRNAs themselves are degraded by our cells in a matter of days, so I do not find any reason to think that the mRNAs delivered to cells in our arm muscle would have a direct effect on proteins in the brain.”
Vincent Racaniello, professor of microbiology and immunology at Columbia University, called the claim that messenger RNA vaccines produced by Pfizer/BioNTech and Moderna could lead to an increase in prion disease is “completely wrong,” and that Classen’s article is “flawed.” In an email to The Dispatch Fact Check he said: “The study by Classen is a theoretical exercise in which he assesses if the mRNA vaccine can convert cell proteins to prion conformations. The exercise iscompletely speculative and flawed and no conclusions can be drawn from this study. Hence the claims on social media are completely wrong as they are based on a flawed study from which no conclusions can be made.”
https://factcheck.thedispatch.com/p/could-the-mrna-vaccines-lead-to-an
"mRNA vaccines have a longer history of testing in humans that started several years before the COVID vaccines"
That's not true. Only 20 people got an mRNA vaccine before covid-19, and 2 died.
Animal studies have gone on since 1990. mRNA vaccines have been tested in humans before, for at least four infectious diseases: rabies, influenza, cytomegalovirus, and Zika.
The technology has been used not just in vaccines for infectious diseases, but also as a means to rev up the immune system to battle cancer. mRNA can target tumor-associated antigens expressed mainly by cancerous cells, like certain growth factors. These therapeutic -- rather than prophylactic -- vaccines have been tested in a range of cancers, including acute myeloid leukemia, multiple myeloma, glioblastoma, melanoma, prostate cancer, and others.
https://www.medpagetoday.com/infectiousdisease/covid19/89998
You can read the real history of mRNA therapies on this complaint:
https://smallpdf.com/result#r=25e08a09d4b932b44f4b40649ea99e24&t=share-document