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CuomoisaMassMurderer 29 points ago +29 / -0

Crippling arthritis symptoms are one possible impact of Lyme disease. I didn't used to be an anti-vaxxer generally, but the more you look into it ...

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snowypepe 31 points ago +31 / -0

To know that many vaccines are total garbage, you just have to look at the media spin of “anti-vaxxers”.

Honestly if you just do the opposite of everything the media tells you to do, you will live a pretty healthy life.

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Wankerton 18 points ago +18 / -0

Some vaccines might be viable. But humanities desperate desire to get rid of diseases leads us to absurd "cures"

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Nimblenavigator1 [S] 5 points ago +5 / -0

I’m not categorically anti vaccine. I was vaccinated as a kid, and I still get my annual flu shot. No issues. Those are generally well proven, have a good risk:reward ratio, studied and refined over the course of decades. I’ve done my diligence, and am comfortable with it. Not a blind or coerced decision.

By contrast, COVID vaccines are not FDA approved. They were rushed to market, and are the first real use of an mRNA vaccine. We have zero clue about the long-term effects; the immediate day or two after are shit. All this risk and coercion, but to what end? Objectively speaking, it’s an insanely stupid risk to assume for a virus with a 99.7% survival rate.

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CuomoisaMassMurderer 1 point ago +1 / -0

Agreed! And some groups have a survival rate considerably higher than 99.7%, assuming infection with CCPvirus and no medical care whatsoever.

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DisbandTheCIA 17 points ago +17 / -0

A vaccine for lyme without infection is as fucking stupid as a vaccine for rabies without an animal bite.

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thelastlast 8 points ago +8 / -0

exactly.

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Nimblenavigator1 [S] 12 points ago +12 / -0

Conclusion from a case study on the drug:

As we ask how to weigh public health benefits of interventions against potential risks (notably incurred by identifiable individuals), the LYMErix™ case illustrates that media focus and swings of public opinion can pre-empt the scientific weighing of risks and benefits in determining success or failure.

So remember to trust The Science! ™

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870557/#!po=58.1633

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KeeptheChief 8 points ago +8 / -0

Why would you need a vaccine for Lyme disease? Is it really widespread enough to need a vaccine instead of just treating people who get it?

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Big_Sam_Handwich 5 points ago +5 / -0

Lyme disease can really destroy your health long term. It's hard to fix if you got catch it early. In my area deer ticks are really bad....I personally know many people with long term damage from Lyme disease. I do landscaping and find them on me often...always have to be checking for them.

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zooty 5 points ago +5 / -0

Some people are much more at risk than others and the symptoms if you don't catch it in time can be really debilitating. Certainly not something you would expect everyone to have but if it was safe and effective, there would be more than a few people it would be appropriate for.

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deplorablebot 4 points ago +4 / -0

It can be treated very effectively with antibiotics if identified in time. The issue is that it is not always easy to diagnose because of various presentations that mimic other diseases. Bottom line, if you ever have a tick latch onto you, take a picture of it, do your best to remove it without pulling it apart. If you think you may have left anything behind get a doctor to prescribe antibiotics prophylactically, and certainly if you develop a rash and/or other symptoms.

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zooty 3 points ago +3 / -0

Yep. We have special tick tweezers though any tweezers that allow you to grip the head firmly without squeezing the body will work.

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morememesplz 1 point ago +1 / -0

Why can't you squeeze the body??? Sounds gross though...

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kt524 1 point ago +1 / -0

To try and keep it from squeezing anything back into the bite would be my assumption.

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2008RonPaul2012 1 point ago +1 / -0

The head can disconnect from the body, leaving it stuck inside the skin.

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zooty 1 point ago +1 / -0

Their head is like a little syringe inserted into your circulatory system. Squeezing the body can cause yuk to enter your system. I'm not sure how factual this is but it sounds reasonable.

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KeeptheChief 3 points ago +3 / -0

I see. I didn't know that, thanks.

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zooty 3 points ago +3 / -0

No problem. I'm not as outdoorsy as some but I am a bit and it's always a concern when you find them on you. I still have one in the freezer that I found on my son (though the time for concern is long past. I need to throw it out).

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SuddenlyClintoned 1 point ago +1 / -0

Would be handy if it worked for outdoorsy professions. (tree planter, feller, pipeline, even général construction?)

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sleazysaxsolo 6 points ago +6 / -0

Isn’t lyme treated with antibiotics? Why would there be a vaccine anyways?

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Big_Sam_Handwich 5 points ago +5 / -0

Only if caught early on.

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ThisClaimIsDisputed 4 points ago +4 / -0

people need to understand that this vaccine is still administered to dogs, controversially, and vets know about it's potential to cause autoimmune arthritis, particularly in retrievers.

part of the bacterial protein in the vaccine causes the body to make antibodies that cross react with healthy tissues in a subset of vaccine recipients. this leads to antibodies attacking healthy tissue and over time develops into an autoimmune condition. it took over a year for symptoms to develop in the people who originally received the Lyme vaccine.

"Following infection with B. burgdorferi, people with the human leukocyte associated antigen (HLA) type DR4+ genotype (HLA-DRB1*0401) might experience increased risk of developing chronic treatment-resistant arthritis. These patients produce high levels of autoantibody to OspA in their synovial fluid [31]. Laboratory experiments found a striking resemblance between the immunodominant epitope of OspA, in the context of DR4+, to peptides within the leukocyte integrin LFA-1. Indeed, patients with treatment-resistant Lyme arthritis, but not other forms of chronic arthritis, demonstrated autoreactivity against LFA-1 [32]. Although more recent studies suggest that LFA-1 does not represent the relevant autoantigen [33], OspA antibodies might react against other, as yet unidentified, autoimmune targets.

These findings suggested that, in patients with the DR4+ genotype, an immune response against OspA could translate into a cross-reactive autoimmune response. By implication, an OspA Lyme vaccine might result in autoimmunity in these genetically predisposed individuals. Although causality proved difficult to demonstrate, one study reported four male patients with the DR4+ genotype who developed autoimmune arthritis after receiving LYMErix™ vaccine [34].

Differential genetic susceptibility applied to immunization risk represents a new concept. Although the clinical importance of the DR4+ genotype to a person receiving an OspA Lyme vaccine remains incompletely understood, some suggest screening recipients for HLA type DR4+ and vaccinating only non-carriers. However, genetic screening would add significantly to the costs of a vaccination programme, shifting the cost-benefit ratio towards only the patients at the highest risks of acquiring Lyme disease. However, this approach might limit the potential risks from a vaccine with demonstrated ability to provide more good than harm for the majority of the population."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870557/

the covid vaccines also have this potential. people don't understand that the virus itself isn't the only thing that can harm us. the spike proteins alone have been shown to damage lungs ( https://medicalxpress.com/news/2021-04-sars-cov-spike-protein-lung.html ) and cross the blood brain barrier ( https://www.nature.com/articles/s41593-020-00771-8 ) , even in the absence of viral replication.

so why would they develop a vaccine that instructs the body to make a spike protein that, by itself, is harmful?

then learn about the antibodies that we make to COVID and the antibody therapy used to treat COVID. well it turns out that they crossreact with 28 different human tissues.

https://www.frontiersin.org/articles/10.3389/fimmu.2020.617089/full

so we are giving our bodies a spike protein that causes damage and then making antibodies that attack our own tissues.

wake up...

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deleted 1 point ago +1 / -0
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Snerdley 1 point ago +3 / -2

as much as I want to believe this and spread it, a little research shows it was pulled because of perceived arthritis link, and dwindling sales. No actual arthritis was ever shown in humans. Careful spreading this amongst those who will look into it.

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ThisClaimIsDisputed 6 points ago +6 / -0

arthritis in humans was always denied by the manufacturer but it is common knowledge among vets that it can cause arthritis in dogs, especially retrievers. it has been shown in animal studies to cause arthritis in rats and hamsters.

the mechanism by which it causes arthritis is some of the proteins in the vaccine, derived from the bacteria, cause some people's bodies to develop antibodies that crossreact with other tissues. this leads to an autoimmune conditions where the body inflamed its own joints...arthritis.

the covid vaccine also has the potential to do this as the antibodies to the spike protein, which our bodies are instructed to make by the mRNA, can crossreact with human tissues.

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Nimblenavigator1 [S] 1 point ago +1 / -0

It’s well off patent at this point. So why is Pfizer spending millions and millions to develop a Lyme vaccine when it would be far cheaper to skip the R&D and spend a fraction on marketing?

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deleted 1 point ago +1 / -0