They are setting up the testing to get failure by any means necessary.
^ This.
That's why the 2 or 3 clinical studies that everyone found so "disappointing" had the results they had. They 1) waited too late in the disease process to start and 2) almost deliberately designed the study to test an effect that we know HCQ can't possibly achieve.
The theory is that if it acts as a zinc ionophore inhibiting viral replication (which we have evidence of) or changes the pH internally to the cell, both of these must be achieved prior to infection. That everyone seems to have a fetish for testing HCQ on already sick patients admitted to the ICU suggests that either the researchers are stupid (unlikely) or deliberately modifying the study to obtain the results they want (likely).
^ This.
That's why the 2 or 3 clinical studies that everyone found so "disappointing" had the results they had. They 1) waited too late in the disease process to start and 2) almost deliberately designed the study to test an effect that we know HCQ can't possibly achieve.
The theory is that if it acts as a zinc ionophore inhibiting viral replication (which we have evidence of) or changes the pH internally to the cell, both of these must be achieved prior to infection. That everyone seems to have a fetish for testing HCQ on already sick patients admitted to the ICU suggests that either the researchers are stupid (unlikely) or deliberately modifying the study to obtain the results they want (likely).