For HD, I prefer a good .223/5.56 defensive load. Specifically Federal Tactical Bonded. Speer .223 Gold Dot are another excellent choice as well.
The terminal performance is much much better than any pistol cal, less risk of over penetration, and you get the control of a rifle, more ammo, and faster follow up shots.
Speer Gold Dot in 9mm is the perfect HD round.
For HD, I prefer a good .223/5.56 defensive load. Specifically Federal Tactical Bonded. Speer .223 Gold Dot are another excellent choice as well.
The terminal performance is much much better than any pistol cal, less risk of over penetration, and you get the control of a rifle, more ammo, and faster follow up shots.