There is no right combo with the types of drugs they've got him on. It's a balancing act, and the tipping point changes every day. If he slept well one night, the dose from the previous day when he didn't might make him hyper and irritable. That doesn't even get into tolerance stacking, cumulative use side effects, and the quagmire of issues that can be caused by multiple drugs.

If they can keep him upright and nominally functional for 8 hours a day, that's probably cause for celebration.