What insight? Moderna has stated that they've had the ability to synthesize mRNA based off genetic sequencing for a while, and they were able to generate what was needed to produce the proteins on SARS-CoV-2 receptors back in January. What took so long was the clinical trials, because we've never used an mRNA vaccine before using the novel transport mechanism they have.
But the ironic thing is that mRNA therapy as a research program started as a potential cancer treatment. So I guess if you wanted to suggest that was the "existing insight," then you're right, but it didn't start with coronaviruses.
If he were, we might have an idea which concept he was attempting to convey.
But alas, it may forever remain a mystery.
u/NuclearOption isn't wrong though. See my sibling post for citations.
mRNA vaccines cannot modify DNA. mRNA can only be used to transcribe proteins by the ribosomes in the cellular cytoplasm. It cannot enter the nucleus.
The dangers with the Pfizer and Moderna vaccines lie in their use of polyethylene glycols to stabilize the lipid nanoparticles for transport into the cell. People are reacting to these, and if the anaphylaxis isn't treated rapidly, they can die.
Not everyone reacts to PEG, however, but I'd suggest reading my sibling post if you want a) citations and b) commentary on a COVID vaccine that absolutely is concerning.
I'm not saying to trust them; I'm saying that's how biology works. mRNA cannot modify genes and the only thing it does is produce proteins. That's it.
Where I would direct my concern with these vaccines is toward the PEG-stabilized lipid nanoparticles, because PEG absolutely can kill people if they have a reaction to it. Based on the data that's currently available, it appears that there are a growing number of patients exhibiting anaphylaxis post-vaccination.
Given the misinformation floating around here, I wouldn't be surprised if he's trying to claim that COVID has been around a lot longer than we think.
But it's possible he's referring to the coronavirus research that was done decades ago during the original SARS-CoV outbreak. There's where we found that HCQ appeared to be effective in managing the disease process by action as a zinc ionophore.
Which indicates that the disinformation campaign against HCQ not only went against established research from ~2005 but was almost certainly criminal and resulted in more deaths.
The Pfizer and Moderna vaccines are mRNA vaccines. mRNA does not enter the cell nucleus--it remains in the cytoplasm. There is a paper that studied how mRNA synthesized in the nucleus diffuses into the cytoplasm (after transcription) which may be worth reading. mRNA is used by ribosomes in the cytoplasm to synthesize proteins, enzymes, and other bits--it's how the virus produces more virions with the exception that the mRNA fragments used by both of these vaccines are the sequences that produce the surface receptors.
You cannot modify DNA from mRNA.
What's making people sick in these vaccines is the polyethylene glycol used to stabilize the lipid nanoparticles that encapsulate the mRNA as its delivery system, and PEG are known to cause anaphylaxis. PEG as a component of vaccines is not well-studied and should be viewed with caution, because it certainly does provoke an immune response that can be dangerous if not outright lethal.
If you wanted to go down the rabbit hole of a vaccine that could feasibly modify the patient's DNA, then I'd suggest looking into the AstraZeneca vaccine which uses a modified adenovirus (DNA virus) to inject DNA into the nucleus where the cell transcribes mRNA from the DNA. There's a YouTuber who used a similar adenovirus to "cure" his lactose intolerance for a couple of years by modifying his own DNA in intestinal tissue responsible for producing lactase. Except that the effect wasn't permanent because the modifications could not be transcribed to the daughter cells.
Oh, true.
I guess I can't say he's a complete failure. Just that he's a major success... for China.
He never knew anything about COVID from the start. He's been in charge of the allergies and infectious diseases dept. for something like 30 years.
...and accomplished what, exactly?
Faux-ci is useless!
It's true. They only know how to destroy, not create.
>when your outie becomes an innie through diet alone
There's absolutely a point in time where you have to pass the torch on to the next generation(s) willing to fight.
I admire u/Doth 's tenacity, but it's not for everyone.
Let us fight the war now. It's time. We're younger. You and your husband deserve a break.
"Help me find a full auto adapter"
"lmao bro u can't drive a stick?"
Not if you're chewing to assert dominance.
I still can't believe someone would be this stupid.
But then I look at who the Dems were running for their candidate(s) and get a harsh dose of reality.
Also not icons because some of them are getting so fat they're hard to drag-and-drop.
And making memes a felony.
This bastard wins the prize.
Funny thing is that this is exactly what the fractional voting as implemented in the Dominion machines accomplishes when votes are considered to be not-whole-numbers.
So it's half-assed?
I agree.
There should've been enough to have a rope shortage. Or enough to make C++ developers jealous.
Or at least be creative: "I was asking what she charged so I have an idea how cheaply Swallowwell sold the country out when he fucked us."
source?
Earlier today. Look on the front page and scroll down a bit. In particular this thread.
CC companies and payment processors should've been fined HEAVILY years ago for dropping alt media for nothing other than "their opinions scare us because the left might call us bad names."
There should have been legislation resolving this a long time ago. It's not even a free speech issue. Depriving someone of their own economic participation for no other reason than difference of opinion should have resulted in hangings. But, I'm known to take things a little far sometimes.
...mostly because drawing and quartering isn't legal.
My personal philosophy is that he's exhausting all legal options before bringing out the hammer. And potentially running the clock out on them just the same as they've been trying with us.
This is just speculation. My optimism is a lot lower than it was, but the reality that we need to prepare for is the fact we almost certainly won't know the outcome of all of this until the day before or the day of the inauguration.
I'm OK with this.